Senna alata
 

Neamsuvan, O., T. Tuwaemaengae, F. Bensulong, A. Asae and K. Mosamae. 2012. A survey of folk remedies for gastrointestinal tract diseases from Thailand's three southern border provinces. J Ethnopharmacol. [Epub ahead of print].

Abstract:

Ethnopharmacological relevance: Gastrointestinal tract diseases commonly occur in Thailand. However, surveying for finding out traditional drugs has never been done. Aim of study: To quantify and categorize the folk medicinal remedies that are used for healing the gastrointestinal tract by the traditional healers living in Thailand's three southern border provinces. Materials and methods: The Pattani, Yala and Narathiwat provinces were selected. Semi-structured interviews of nine healers were conducted to collect information that included the remedy names, herbal ingredients, plant parts used, preparation, properties and treatment methods. The data were then further analyzed. Result: The results revealed that 39 multi-species remedies and 36 single-species remedies were used to treat gastrointestinal disorders. A total of 103 plant species and 5 other materia medica were used as therapeutics. Most of the plants used were of the Zingiberaceae, Fabaceae and Euphorbiaceae families. Furthermore, it was found that although most of the healers used different remedies for a particular disease, some of the ingredients might have been similar. For example, Caesalpinia bonduc (L.) Roxb. was an ingredient used for parasitic disease remedies, and Senna alata (L.) Roxb. was used for constipation remedies. Conclusion: A review of the literature revealed 57 plant species and 2 other materia medica that have already been tested for their biological activities, whereas 46 plant species and 3 materia medica have never been tested. Consequently, research should be performed to confirm the pharmacological properties of folk remedies.

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Hennebelle, T., B. Weniger, H. Joseph, S. Sahpaz and F. Bailleul. 2009. Senna alata. Fitoterapia, 80: 385–393.

Abstract ; A review is made of chemical, ethnopharmacological and pharmacological papers dealing with Senna alata (L.) Roxb.,a plant that belongs to the Creole traditional system of medicine and that has recently been introduced in the French Pharmacopoeia. The proofs existing for its various usages are presented. The species is mainly used against constipation and skin diseases. The laxative activity is supported by scientific findings. In contrast the dermatologic use requires further investigation. The species can be considered as safe for short-term or topical use.

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ELUJOBA, A. A., O. O. AJULO and G. O. IWEIBO. 1989. Chemical and biological analyses of Nigerian Cassia species for laxative activity. Journal of Pharmaceutical Biomedical Analysis 7, 12: 1453-1457.

Abstract: The leaves of 10 Cassia species (Leguminosae), cultivated in Nigeria, were assayed spectrophotometrically for combined anthraquinone content and also pharmacologically for their laxative properties in male albino rats using official senna leaves (Cassia acutifoliu Del.) as the reference standard. Leaves of C. podocarpa Guill. and Perr. and of senna had identical laxative potency. The results of both the chemical and the biological experiments suggested that C. alata L. and C. podocurpa are the most likely candidates for drug development in Nigeria. The use of a laxative index is proposed for the comparative study of Cassia (or any plant species) and its possible application to the quality control of these drugs is discussed.